Publications by authors named "E C Whang"
Objective: Concerns exist about clinical and operative skill decay in surgery residents when they dedicate time away from clinical training to pursue research. However, it remains undetermined how to best prevent these negative impacts. Our study evaluated the perspectives of surgical research residents on interventions to improve their reentry into clinical training.
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- * The study reveals that hepatocytes are the main producers of lipopolysaccharide binding protein (LBP), which is implicated in liver inflammation but does not significantly affect liver fibrosis.
- * Research indicates that targeting inflammation through LBP might not effectively reduce liver fibrosis, challenging the current strategies aimed at managing MAFLD.
Article Synopsis
- The study investigates how Aster-A, a cholesterol transporter, affects membrane cholesterol levels in T cells and their immune function.
- Aster-A is recruited to the plasma membrane during T cell activation, facilitating the removal of excess cholesterol, which is crucial for proper T cell receptor signaling and function.
- Without Aster-A, T cells accumulate excess cholesterol, leading to enhanced immune responses and changes in nutrient absorption, contributing to resistance against obesity.