Publications by authors named "E C Royston"
Article Synopsis
- Letermovir is used for preventing cytomegalovirus (CMV) in patients who have received hematopoietic stem cell transplants (HSCT), and its therapeutic drug monitoring (TDM) was studied for effectiveness and practicality.
- A study involving 40 adult patients found that letermovir levels in the blood remained stable for 70 days after treatment, but there was significant variability among patients.
- The presence of certain medications, such as posaconazole and cyclosporine, increased letermovir levels, while no clear links were found between these levels and the incidence of breakthrough CMV infections.
Letermovir prophylaxis in allogeneic hematopoietic cell transplant recipients significantly reduces the incidence of clinically significant cytomegalovirus infection. However, breakthrough infections still occur despite adequate prophylaxis. In the present retrospective cohort study, we identified clinically relevant predictive factors for clinically significant CMV breakthrough infection during letermovir prophylaxis.
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- A study explored the effectiveness of letermovir as a preventive treatment for cytomegalovirus (CMV) infection in patients who underwent high-risk allogeneic hematopoietic cell transplantation (HCT).
- Results showed that letermovir significantly reduced the incidence of clinically significant CMV infections from 82.7% in untreated controls to 34.5% in patients receiving the drug, along with shorter treatment durations and potential cost savings.
- The administration of letermovir also correlated with improved platelet counts and renal function, suggesting additional benefits that warrant further research.
With continued technologic advances, it is not surprising that gaming techniques are increasingly being used in radiology residency programs. This comprehensive review on gaming in radiology education offers insight into the importance of gaming, types of games and principles utilized in gaming, as well as applications that are inherent in artificial intelligence and continued medical education. The advantages and disadvantages of gaming will be considered, as well as barriers to successful adoption of gaming.
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