Publications by authors named "E C Obi"
The impact of ABO blood group on the prevalence of transfusion-transmitted infections among blood donors in a tertiary-care hospital.
Am J Clin Pathol
January 2025
Objectives: Transfusion-transmitted infections are a serious complication of blood transfusion. Devising a means of detecting at-risk blood donors may be beneficial in low- and middle-income countries such as Nigeria. We sought to determine the impact of ABO blood group on the prevalence of transfusion transmitted infections.
View Article and Find Full Text PDFComparative Efficacy of Continuous Positive Airway Pressure and Antihypertensive Medications in Obstructive Sleep Apnea-Related Hypertension: A Narrative Review.
High Blood Press Cardiovasc Prev
December 2024
Introduction: Obstructive sleep apnea (OSA) presents a significant global health concern, affecting a substantial portion of the population, particularly among young and middle-aged adults.
Aim: This review aims to assess the efficacy of continuous positive airway pressure (CPAP) compared to antihypertensive medications in managing OSA-related hypertension.
Methods: A comprehensive literature search was conducted across multiple databases, yielding studies published from 2000 to March 2024 that investigated CPAP, antihypertensives, or their combination therapy in OSA patients.
Article Synopsis
- - The study investigated how early growth (EG) and the timing of maximum growth during puberty (I2) affect the development and efficiency of broiler breeder females by adjusting their body weight (BW) targets based on a Gompertz model.
- - Researchers used a factorial design with different I2 levels and two EG treatments, examining various body composition and performance variables in 288 pullets fed in a controlled manner.
- - Results showed that altering EG and I2 influenced BW and feed intake, with EG20 females having better breast fleshing scores, faster sexual maturation, and increased carcass fat deposition compared to EG0.
Antisense Oligonucleotides in Dyslipidemia Management: A Review of Clinical Trials.
High Blood Press Cardiovasc Prev
October 2024
Article Synopsis
- * This review evaluates the effectiveness and safety of antisense oligonucleotides (ASOs) for treating dyslipidemia and explores their potential in personalized medicine for at-risk patients.
- * Clinical trials suggest that ASOs like Mipomersen and Volanesorsen may be more effective than traditional statins, offering fewer side effects and serving as alternative treatments for patients with inherited lipid disorders.
Health Facility Capacity and Health-care Worker Knowledge, Attitudes, and Practices of Hepatitis B Vaccine Birth-dose and Maternal Tetanus-Diphtheria Vaccine Administration in Nigeria: A Baseline Assessment.
Ann Afr Med
October 2024
Background: Hepatitis B virus (HBV) and neonatal tetanus infections remain endemic in Nigeria despite the availability of safe, effective vaccines. We aimed to determine health facilities' capacity for hepatitis B vaccine birth dose (HepB-BD) and maternal tetanus-diphtheria (Td) vaccination and to assess knowledge, attitudes, and practices of HepB-BD and maternal Td vaccine administration among health facility staff in Nigeria.
Materials And Methods: This was a cross-sectional study assessing public primary and secondary health facilities in Adamawa and Enugu States.