Publications by authors named "E C Lins"
Ayahuasca Pretreatment Prevents Sepsis-Induced Anxiety-Like Behavior, Neuroinflammation, and Oxidative Stress, and Increases Brain-Derived Neurotrophic Factor.
Mol Neurobiol
November 2024
The psychoactive decoction Ayahuasca (AYA) used for therapeutic and religious purposes by indigenous groups and peoples from Amazonian regions produces anti-inflammatory and neuroprotective effects. Thus, it may be useful to attenuate the neuroinflammation and related anxiety- and depressive-like symptoms elicited by inflammatory insults such as sepsis. Rats were pretreated for 3 days with different doses of AYA.
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- PAD (Peripheral Arterial Disease) can lead to Critical Ischemia (CI) of the Lower Limbs, often resulting in amputation, and Infrared Thermography (IT) is a non-invasive method to assess skin temperature for guiding amputation levels.
- A study conducted between April and November 2023 at Hospital de Base do Distrito Federal evaluated patients with PAD and CI in preoperative stages, utilizing IT to monitor thermal gradients.
- Findings indicated that smoking patients exhibited greater thermal gradients and were more inclined to require above-the-knee amputations, demonstrating IT's effectiveness in the preoperative assessment of amputation levels.
Resistance Index as a Prognostic Factor for Patency in Distal Lower Limb Arterial Revascularization.
Ann Vasc Surg
February 2025
Background: Critical limb ischemia (CLI) of the lower limbs (LLs) is a severe condition caused by peripheral arterial obstructive disease (PAOD). Surgical planning for CLI requires the study of limb circulation, and the vascular resistance index (RI) measured by Doppler ultrasound (US) has been used to aid in surgical decision-making. The objective is to correlate the RI of recipient arteries with the patency of LL revascularization surgeries in patients with CLI.
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- There is a growing concern over the lack of effective treatments for mild cognitive impairment (MCI), which is increasingly prevalent due to an aging population, and transcranial photobiomodulation (t-PBM) using near-infrared light may offer a solution.
- The study evaluated various cognitive and emotional outcomes in 93 older adults with MCI, comparing those receiving t-PBM therapy to a placebo group, over a period of 150 days.
- Results showed that t-PBM significantly enhanced cognition scores and increased levels of the neuroplasticity biomarker BDNF, indicating a potential therapeutic benefit for individuals with MCI.
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- The study aimed to assess changes in the great saphenous vein (GSV) and its tributaries following endovenous laser ablation (EVLA) with a focus on hemodynamic and anatomic outcomes.
- A total of 112 areas in 28 legs from 25 patients were analyzed before and three months after the procedure, revealing significant reductions in GSV diameter and tributary diameters across all regions studied.
- Post-treatment, the number of refluxing tributaries decreased significantly, and the overall condition of patients improved as shown by a notable drop in the Venous Clinical Severity Score (VCSS).