Publications by authors named "E C Jacobs"
Ceftriaxone-resistant Enterobacterales remain a public health threat; contemporary data investigating their molecular epidemiology are limited. Five hundred consecutive ceftriaxone-resistant (MIC ≥ 4 µg/mL) Enterobacterales bloodstream isolates were collected between 2018 and 2022 from three Maryland hospitals. Broth microdilution confirmed antibiotic susceptibilities.
View Article and Find Full Text PDFBackground: Access to healthcare is a major challenge in South Sudan, but evidence on the factors influencing health seeking behaviour (HSB) and the magnitude of their effect is limited. This study aims to identify which determinants are associated with seeking care for perceived health needs and with seeking care at private or public healthcare facilities in South Sudan.
Methods: A cross-sectional household survey was conducted in three purposefully-selected states (Central Equatoria, Western Equatoria and Warrap).
Article Synopsis
- The effectiveness of ceftriaxone in determining susceptibility to newer oral cephalosporins is uncertain.
- In a study of 409 bloodstream isolates of Enterobacterales, ceftriaxone susceptibility correlated with high rates of susceptibility to cefuroxime (89%), cefdinir (86%), cefpodoxime (90%), and cefixime (94%).
- When focusing only on isolates that were susceptible to ceftriaxone, the susceptibility rates for the four oral cephalosporins increased to between 92% and 99%.