Publications by authors named "E C Hobbs"
Quantitative dynamic contrast-enhanced (DCE) MRI as a promising method for the prediction of breast cancer response to neoadjuvant chemotherapy (NAC) has been demonstrated mostly in single-center and single-vendor platform studies. This preliminary study reports the initial experience in implementing quantitative breast DCE-MRI in multi-center (MC) and multi-vendor platform (MP) settings to predict NAC response. MRI data, including B mapping, variable flip angle (VFA) measurements of native tissue R (R), and DCE-MRI, were acquired during NAC at three sites using 3T systems with Siemens, Philips, and GE platforms, respectively.
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- Buruli ulcer (BU) is a neglected tropical disease caused by the bacterium Mycobacterium ulcerans, primarily affecting skin and subcutaneous tissue, with transmission dynamics varying by geographic area, particularly in endemic regions like Victoria, Australia.
- In a study conducted in Melbourne and Geelong, researchers conducted necropsies and surveillance on possums, revealing that 77% of the 26 examined possums were common ringtails, with 9 showing cutaneous ulcers and 73% testing positive for M. ulcerans DNA, indicating a significant reservoir in these animals.
- The findings suggest that possums may contract BU through bites from infected mosquitoes, environmental sources, or wounds, highlighting the need for a One Health approach to
Article Synopsis
- Buruli ulcer (BU) is a skin disease caused by the bacterium Mycobacterium ulcerans, which is increasingly seen in Australia where possums serve as a reservoir for the infection.
- In a study, six wild-caught possums that had never been exposed to MU were injected and all developed BU, with ulceration occurring between 49 and 77 days after infection.
- The findings revealed systemic infection signs in most possums, indicating that this model can enhance understanding of how the bacterium spreads and can inform strategies to prevent further transmission and outbreaks.
The standard of care for pediatric patients with severe obesity considering metabolic and bariatric surgery is a preoperative multidisciplinary evaluation. A multidisciplinary team allows for the efficient use of variable personnel expertise to evaluate, manage, and support a pediatric patient and family through metabolic and bariatric surgery. This review discusses the purpose, recommended team members, patient selection, content, and benefits of the multidisciplinary preoperative evaluation.
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