Publications by authors named "E C Craciun"
(1) Birth asphyxia is a major cause of delivery room resuscitation. Subsequent organ failure and hypoxic-ischemic encephalopathy (HIE) account for 25% of all early postnatal deaths. The neonatal sequential organ failure assessment (nSOFA) considers platelet count and respiratory and cardiovascular dysfunction in neonates with sepsis.
View Article and Find Full Text PDFThe use of gentamicin (GM) is limited due to its nephrotoxicity mediated by oxidative stress. This study aimed to evaluate the capacity of a flavonoid-rich extract of L. elderflower (SN) to inhibit lipoperoxidation in GM-induced nephrotoxicity.
View Article and Find Full Text PDFThere is evidence to suggest that abnormal angiogenesis, inflammation, and fibrosis drive diabetic nephropathy (DN). However, there is no specific treatment to counteract these processes. We aimed to determine whether DIAVIT, a natural Vaccinium myrtillus (blueberry) and Hippophae Rhamnoides (sea buckthorn) extract, is protective in a model of type II DN.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to create two cost-effective rat models of inflammatory bowel diseases (IBD) using dextran sodium sulfate (DSS) and 2, 4, 6-trinitrobenzene sulfonic acid (TNBS) to better understand the diseases.
- Researchers assessed the impact of these compounds on oxidative stress, particularly looking at glutathione peroxidase (GPx) activity, and compared the resulting histological changes in the rats' colons.
- Both models produced characteristics similar to human conditions, showing that DSS and TNBS can be reliable for studying acute inflammation in IBD.