Research on the impact of artificial intelligence technology on urban public health resilience.

Urban public health resilience has become a critical focus in the transition to high-quality development, especially in addressing increasing public health challenges. This study explores the role of artificial intelligence (AI) technology in enhancing urban public health resilience across 284 Chinese cities from 2011 to 2021. Using a comprehensive index based on resistance, recovery, and innovation dimensions, the study quantifies AI technology levels through patent applications and authorizations, further disaggregating these into invention, utility model, and design patents.

Neuron-inspired CsPbBr/PDMS nanospheres for multi-dimensional sensing and interactive displays.

Multifunctional materials have attracted tremendous attention in intelligent and interactive devices. However, achieving multi-dimensional sensing capabilities with the same perovskite quantum dot (PQD) material is still in its infancy, with some considering it currently challenging and even unattainable. Drawing inspiration from neurons, a novel multifunctional CsPbBr/PDMS nanosphere is devised to sense humidity, temperature, and pressure simultaneously with unique interactive responses.

Advances in the relationship of immune checkpoint inhibitors and DNA damage repair.

Cancer immunotherapy, alongside surgery, radiation therapy, and chemotherapy, has emerged as a key treatment modality. Immune checkpoint inhibitors (ICIs) represent a promising immunotherapy that plays a critical role in the management of various solid tumors. However, the limited efficacy of ICI monotherapy and the development of primary or secondary resistance to combination therapy remain a challenge.

H3K14la drives endothelial dysfunction in sepsis-induced ARDS by promoting SLC40A1/transferrin-mediated ferroptosis.

Pulmonary endothelial cell (EC) activation is a key factor in acute respiratory distress syndrome (ARDS). In sepsis, increased glycolysis leads to lactate buildup, which induces lysine lactylation (Kla) on histones and other proteins. However, the role of protein lactylation in EC dysfunction during sepsis-induced ARDS remains unclear.