Publications by authors named "E C Amaechi"

A number of vector-borne diseases are known to affect humans in tropical and sub-tropical regions of the world. Lymphatic filariasis is one of such debilitating disease caused by a nematode, The present study assessed the prevalence of lymphatic filariasis by screening individuals with filariasis test strip and clinical examination. A sample of 765 consenting individuals were screened for filarial antigenemia using filariasis test strip and clinical examination and interviewed for knowledge and perception of filariasis using a structured questionnaire.

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  • Heart failure is a major global health issue, and managing it effectively is crucial for improving patient outcomes and lowering healthcare costs, with ACE inhibitors and ARBs being common treatments.
  • A study using a decision-analytic Markov model aimed to compare the cost-effectiveness of ACE inhibitors and ARBs, considering medical costs and health outcomes for patients with heart failure.
  • Results indicated that ACE inhibitors had lower costs and slightly better health outcomes (quality-adjusted life years) compared to ARBs, with the findings remaining consistent across various sensitivity and subgroup analyses.
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  • Researchers hybridized a human parasitic fluke with a livestock parasite in a lab setting, but the ecological extent of this hybridization is still uncertain in the wild.
  • Analysis of 34.6 million genetic variations from 162 samples across 18 African countries showed a significant genetic divide between northern and southern populations, with no recent hybridization evidence but signs of past admixture events.
  • The study found that while gene flow barriers exist, 15 introgressed genes are becoming fixed in northern populations, and certain genomic regions, especially on sex chromosomes, resist hybridization, highlighting the importance of interspecific hybridization in shaping the genetics of these medically and agriculturally significant parasites.
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Simulation-based training (SBT) has emerged as a transformative approach in medical education, significantly enhancing healthcare professionals' learning experience and clinical competency. This article explores the impact of SBT, tracing its historical development and examining the various types of simulations utilized today, including high-fidelity mannequins, virtual reality environments, standardized patients, and hybrid simulations. These methods offer a safe and controlled environment for students to practice and hone technical and non-technical skills, ultimately improving patient safety and clinical outcomes.

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Hypertension, a prevalent chronic condition characterized by elevated blood pressure, is a significant global health burden, contributing to approximately 7.5 million premature deaths annually. While existing literature predominantly focuses on conventional treatment modalities, this paper offers unique insights into dependable approaches to hypertension management.

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