Universal and Versatile Magnetic Connectors for Microfluidic Devices.

World-to-chip interfacing remains a critical issue for microfluidic devices. Current solutions to connect tubing to rigid microfluidic chips remain expensive, laborious, or require specialized skills and precision machining. Here, we report reusable, inexpensive, and easy-to-use connectors that enable monitoring of the connection ports.

Magnetically functionalized hydrogels for high-throughput genomic applications.

Single-cell genomics has revolutionized tissue analysis by revealing the genetic program of individual cells. The key aspect of the technology is the use of barcoded beads to unambiguously tag sequences originating from a single cell. The generation of unique barcodes on beads is mainly achieved by split-pooling methods, which are labor-intensive due to repeated washing steps.

Robust and rapid partitioning in thermoplastic.

Partitioning is the core technology supporting digital assays. It divides a sample into thousands of individual reactors prior to amplification and absolute quantification of target molecules. Thermoplastics are attractive materials for large scale manufacturing, however they have been seldomly used for fabricating partitioning arrays.

Widely accessible method for 3D microflow mapping at high spatial and temporal resolutions.

Advances in microfluidic technologies rely on engineered 3D flow patterns to manipulate samples at the microscale. However, current methods for mapping flows only provide limited 3D and temporal resolutions or require highly specialized optical set-ups. Here, we present a simple defocusing approach based on brightfield microscopy and open-source software to map micro-flows in 3D at high spatial and temporal resolution.

Editorial for the Special Issue on Droplet Microfluidics.

Emulsions, which are collections of immiscible droplets, have elicited scientific and commercial interests for decades [...