Publications by authors named "E Breda"
Article Synopsis
- - The study focused on pre-professional female adolescent dancers to examine the prevalence of delayed bone maturation and menstrual cycle irregularities, as well as their potential links to low back pain (LBP).
- - Findings revealed that while many dancers experienced delayed bone maturation (32%) or menstrual cycle issues (53%), these conditions were not linked to LBP; however, those with a history of LBP started dancing at a younger age and had noticeable hip rotation differences.
- - The conclusion emphasized that while certain physical impairments were common among the dancers, only early dance training, hip asymmetry, and reduced internal hip rotation were significantly associated with the occurrence of LBP.
Fibrosis is characterized by scarring and hardening of tissues and organs. It can affect every organ system, and so could result in organ failure due to the accumulation of extracellular matrix proteins. Previous studies suggest that mechanical forces (such as shockwave therapy, SWT) initiate a process of mechanotransduction and thus could regulate fibrosis.
View Article and Find Full Text PDFBackground: Despite being a stable component of burn rehabilitation at later stages of recovery, exercise training is not commonly provided during the acute phase of burns. A lack of evidence surrounding its efficacy and safety in severely burned adults has hampered its implementation in acute burn care. The aim of this study was to investigate the capacity of early exercise training to modulate parameters of postburn muscle wasting and quality of life.
View Article and Find Full Text PDFPurpose: This study aimed to investigate the difference in absolute and fat free mass (FFM)-adjusted resting energy expenditure (mREE) and body composition (body weight, fat mass (FM), FFM) between breast cancer survivors (BCs) and controls. Correlations with body composition were analyzed. We examined if survival year, or being metabolically dysfunctional were predictive variables.
View Article and Find Full Text PDFSingle-Agent Trabectedin Versus Physician's Choice Chemotherapy in Patients With Recurrent Ovarian Cancer With -Mutated and/or BRCAness Phenotype: A Randomized Phase III Trial.
J Clin Oncol
May 2024
Purpose: Literature evidence suggests that trabectedin monotherapy is effective in patients with recurrent ovarian cancer (OC) presenting mutation and/or BRCAness phenotype.
Methods: A prospective, open-label, randomized phase III MITO-23 trial evaluated the activity and safety of trabectedin 1.3 mg/m given once every 3 weeks (arm A) in mutation carriers or patients with BRCAness phenotype (ie, patients who responded to ≥two previous platinum-based treatments) with recurrent OC, primary peritoneal carcinoma, or fallopian tube cancer in comparison with physician's choice chemotherapy in the control arm (arm B; pegylated liposomal doxorubicin, topotecan, gemcitabine, once-weekly paclitaxel, or carboplatin).