The Impact of Social Deprivation on Outcomes in Forefoot Surgery.

Background: The impact of social deprivation (SD) on health outcomes is a topic of increasing interest in orthopaedics. There are limited studies and no clear consensus, though, on the impact of SD on outcomes in foot and ankle surgery. Area deprivation index (ADI) is a well-studied and validated surrogate metric for SD.

A hermetically closed sample chamber enables time-lapse nano-characterization of pathogenic microorganisms .

Pathogenic microorganisms, such as pathogenic mycobacteria, pose a global health burden. Studying these organisms is crucial for gaining detailed knowledge about the pathogens and the diseases they cause. To handle pathogenic organisms, specific biosafety measures appropriate to the virulence of the organism must be fulfilled, most importantly ensuring that all manipulations of pathogenic material are performed within a confined environment.

Predicting outcomes of expectant and medical management in early pregnancy miscarriage using machine learning to develop and validate multivariable clinical prediction models.

Objective: To determine whether readily available patient, ultrasound and treatment outcome data can be used to develop, validate and externally test two machine learning (ML) models for predicting the success of expectant and medical management of miscarriage respectively.

Methods: A retrospective, multi-site study of patients opting for expectant or medical management of miscarriage was undertaken. A total of 1075 patients across two hospital early pregnancy units were eligible for inclusion.

Small-Dose Behavioral Treatment Effects: Learning Following 2 Hours of Computer-Based Conversational Script Training in Individuals With Poststroke Aphasia.

Purpose: Optimal dosage parameters are underspecified for aphasia therapy. This study evaluated effects of small doses of conversational script training in individuals with chronic poststroke aphasia.

Method: Ten adults with chronic poststroke aphasia completed 2 hr of computerized conversational script training on two consecutive days via AphasiaScripts.