Publications by authors named "E Brandon Strong"
Migraine affects 10% of adolescents and children. Typical school protocols in the USA require pharmacological medications to be administered by school nurses, often resulting in treatment delays or omissions when migraine attacks occur during school hours. The Remote Electrical Neuromodulation (REN) wearable is an FDA-cleared smartphone-controlled device delivering acute and preventive treatment of migraine attacks in patients aged 8 and above, allowing safe, effective, discreet, and independent usage.
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- Drug-resistant Mycobacterium tuberculosis, especially mutants resistant to isoniazid, creates significant global health challenges due to mutations in the katG gene, affecting a crucial enzyme.
- Researchers employed CRISPRi, transcriptomics, and metabolomics to identify metabolic and transcriptional changes in an isoniazid-resistant katG mutant, revealing new weaknesses in processes like respiration and ribosome biogenesis.
- The study indicates that these identified vulnerabilities could be targeted for therapeutic strategies, offering potential improvements in treatment effectiveness against drug-resistant tuberculosis strains.
Eyes within the marine gastropod superfamily Stromboidea range widely in size, from 0.2 to 2.3 mm - the largest eyes known in any gastropod.
View Article and Find Full Text PDFImportance: Large language models (LLMs) have shown promise in their performance on both multiple-choice and open-ended medical reasoning examinations, but it remains unknown whether the use of such tools improves physician diagnostic reasoning.
Objective: To assess the effect of an LLM on physicians' diagnostic reasoning compared with conventional resources.
Design, Setting, And Participants: A single-blind randomized clinical trial was conducted from November 29 to December 29, 2023.