Publications by authors named "E Bozan"
Is neutropenic fever an obstacle to effective stem cell harvesting?
Asian J Transfus Sci
September 2022
Article Synopsis
- Autologous stem cell transplantation (ASCT) is an effective treatment for hematologic cancers, but some patients can't collect enough stem cells with just G-CSF, leading to the use of chemomobilization.
- In a study of 183 lymphoma and myeloma patients, 43 experienced febrile neutropenia (FN), showing lower preapheresis blood counts and slower platelet and neutrophil recovery post-transplant.
- Despite the challenges posed by FN, sufficient harvesting of CD34+ stem cells remains possible, indicating the need for prompt treatment of FN and possibly more apheresis sessions.
Introduction: Cyclosporine-A (CsA) and post transplantation cyclophosphamide (PTCy) are common agents used for graft versus host disease (GVHD) prophylaxis in Haploidentical hematopoietic cell transplantation (haplo-HCT). However, the impact of CsA cessation timing in the posttransplant setting on clinical outcomes is uncertain. We aimed to investigate the impact of a novel approach that integrated early CsA cessation with PTCy utilization.
View Article and Find Full Text PDFBackground/aim: It wasaimed herein to investigate coronavirus disease (COVID-19) in cancer patients and compare hematological and solid organ cancer patients in terms of the course and outcome of this disease.
Materials And Methods: Data from cancer patients with laboratory-confirmed COVID-19 infection were analyzed retrospectively. Risk factors for poor prognosis and the effect of vaccination on the clinical outcomes of the patients were evaluated.
Article Synopsis
- This study investigates the feasibility and success factors of collecting peripheral blood stem cells (PBSC) from healthy donors on the 4th day of mobilization, instead of the usual 5th day, using G-CSF.
- Data from 141 healthy donors showed that 81.6% had adequate mobilization, with higher CD34+ cell counts linked to successful early collection.
- The researchers developed a predictive model for clinicians considering early collection, highlighting the importance of donor/recipient weight ratio and CD34+ cell count to maximize success rates.
Objectives: To determine the frequency of head and neck lymphadenopathy (LAP) and intraoral findings (non-dental/dental) in patients with newly diagnosed acute leukemia (AL).
Subjects And Methods: Twenty-eight (52.8%) females and 25 (47.