Publications by authors named "E Bongcam-Rudloff"

Article Synopsis
  • Genomic structural variations, especially copy number variations (CNVs), are important for genetic diversity in cattle, yet they have been underexplored in indigenous Ethiopian breeds like Abigar, Fellata, and Gojjam-Highland.
  • The study identified 3,893 CNV regions covering 19.15 Mb of the cattle genome, with notable differences among breeds, and validated a significant portion of these findings.
  • The analysis revealed candidate genes related to adaptation to high altitudes, heat stress, and tick resistance, highlighting the unique genetic traits of these cattle and their potential implications for breeding and conservation.
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Endometritis is an inflammatory disease that negatively influences fertility and is common in milk-producing cows. An in vitro model for bovine endometrial inflammation was used to identify enrichment of -acting regulatory elements in differentially methylated regions (DMRs) in the genome of in vitro-cultured primary bovine endometrial epithelial cells (bEECs) before and after treatment with lipopolysaccharide (LPS) from , a key player in the development of endometritis. The enriched regulatory elements contain binding sites for transcription factors with established roles in inflammation and hypoxia including NFKB and Hif-1α.

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Salmonella is a major bacterial concern for public health globally. Although there are limited documentation on the prevalence of Salmonella species in Cambodia's food chain, some reports indicate that salmonellosis is a severe gastrointestinal infection in its population and especially in children. To investigate the presence of Salmonella spp.

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Article Synopsis
  • Cashmere goats have two types of hair follicles, with the secondary ones producing cashmere, and their growth is affected by seasonal changes in light.
  • The transcription factor Csdc2 is important for the growth and development of these follicles, and its activity varies through different hair growth phases.
  • Research showed that knocking down Csdc2 reduces the growth of certain cells in the follicles, and identified potential target genes that Csdc2 regulates, providing insights for improving cashmere production.
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