Effect of hydrogen peroxide and hyaluronic acid in mouth rinse after third molar extraction: a triple-blind parallel randomized controlled clinical trial.

Objective: The study aimed to investigate the potential beneficial role of hydrogen peroxide (H2O2) and hyaluronic acid (HA) combination formulation in socket healing after third molar surgery. Biomaterials, including mouthwash formulations, were hypothesized to contribute to improved socket healing and reduced post-operative complications.

Patients And Methods: A triple-blinded parallel randomized controlled clinical trial was conducted at a single-center dental hospital in Milan, Italy.

Evaluation of the effectiveness of a novel mouth rinse containing hyaluronic acid and hydrogen peroxide on gingivitis: A randomized pilot controlled trial.

Objective: To evaluate and compare the effectiveness of a mouth rinse with hydrogen peroxide (H O ) and hyaluronic acid (HA) versus a placebo mouth rinse on gingivitis.

Material And Methods: This was a 21-day, double blind, randomized, two-arm parallel allocation placebo-controlled trial of 50 study participants with a diagnosis of plaque-induced gingivitis. Patients were randomly allocated to the test group or the placebo group and were assessed at three time points over the course of the study by the same operator, at baseline (T0), 7 days (T1), and 21 days follow-up (T2).

Salivary biomarkers of neurodegenerative and demyelinating diseases and biosensors for their detection.

Salivary analysis is gaining increasing interest as a novel and promising field of research for the diagnosis of neurodegenerative and demyelinating diseases related to aging. The collection of saliva offers several advantages, being noninvasive, stress-free, and repeatable. Moreover, the detection of biomarkers directly in saliva could allow an early diagnosis of the disease, leading to timely treatments.

Malignancies and Biosensors: A Focus on Oral Cancer Detection through Salivary Biomarkers.

Oral cancer is among the deadliest types of malignancy due to the late stage at which it is usually diagnosed, leaving the patient with an average five-year survival rate of less than 50%. The booming field of biosensing and point of care diagnostics can, in this regard, play a major role in the early detection of oral cancer. Saliva is gaining interest as an alternative biofluid for non-invasive diagnostics, and many salivary biomarkers of oral cancer have been proposed.

In vitro studies evaluating the efficacy of mouth rinses on Sars-Cov-2: A systematic review.

This systematic review aims to evaluate the evidence on the efficacy of mouth rinses on SARS-CoV-2 from in vitro studies. Five electronic databases were searched up to February 2021; no language or time restrictions were used. Two independent reviewers conducted both selection and data extraction processes.