Publications by authors named "E Blezer"
Article Synopsis
- Recent research has created normative growth charts for the brain structure of rhesus macaques, filling a gap in understanding nonhuman primate neurodevelopment.
- The study analyzed 1,522 MRI scans from 1,024 macaques to identify developmental patterns in brain volume, cortical thickness, and surface area throughout their lifespan.
- These findings not only highlight key milestones in macaque brain development but also allow for meaningful comparisons to human brain maturation, providing a valuable resource for future neuroscience studies.
Importance: In 2018, the first online adaptive magnetic resonance (MR)-guided radiotherapy (MRgRT) system using a 1.5-T MR-equipped linear accelerator (1.5-T MR-Linac) was clinically introduced.
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- * It introduces StandardRat, a standardized fMRI acquisition protocol for rats that has been tested across 20 research centers to enhance data integration.
- * The standardized protocol and processing pipeline improve the reliability of detecting functional connectivity patterns and are made publicly available to foster collaboration in the neuroimaging field.
Rationale: Compulsivity often develops during childhood and is associated with elevated glutamate levels within the frontostriatal system. This suggests that anti-glutamatergic drugs, like memantine, may be an effective treatment.
Objective: Our goal was to characterize the acute and chronic effect of memantine treatment on compulsive behavior and frontostriatal network structure and function in an adolescent rat model of compulsivity.