Publications by authors named "E Bigot-Corbel"
Aim: Observational studies in the general population suggest that low concentrations of lipoprotein (a) [Lp(a)] are associated with an increased risk of type 2 diabetes. Here, we aim to determine whether Lp(a) plasma concentration and Kringle-IV (K-IV) repeat polymorphism were associated with new-onset diabetes (NOD) in individuals with prediabetes.
Methods: IT-DIAB is an observational, prospective study including 303 participants with impaired fasting glucose (fasting plasma glucose [FPG]: 110-125 mg/dl) followed annually for 5 years.
Objectives: Hemolysis is a contributor to CS-AKI. Biochemistry analyzers provide a hemolysis index to quantify in vitro hemolysis, a condition that can, for example, affect the accuracy of potassium concentration measurements. We aimed to assess whether the postoperative plasma level of the hemolysis index (HI) could aid the early recognition of patients at risk for cardiac surgery-associated acute kidney injury (CS-AKI) and also to evaluate other hemolysis indicators: plasma carboxyhemoglobin (COHb) and methemoglobin (MetHb).
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- * Male Wistar Han rats were used to induce hemorrhagic shock through controlled blood loss, followed by a phase of low blood pressure, and then treatment with intravenous fluids to mimic patient care.
- * Results showed significant decreases in blood pressure and increases in organ damage markers, establishing this model as a useful tool for further research on potential treatments for hemorrhagic shock.