Cytomegalovirus (CMV) and rubella virus infection during pregnancy. A study of CMV and rubella virus antibodies in 2014 pregnant women and follow-up studies of infants at risk for intrauterine CMV infections.

Two blood samples, one in the first and one in the third trimester, were collected from 2014 pregnant women. Serological tests for CMV and rubella antibodies were performed in the paired samples. Seroconversion by the CF test for CMV antibodies was demonstrated in 15 women.

Mitogen-induced multiplication of lymphocytes from newborn infants.

Marked lymphocyte responses to PHA, ConA and PWM were demonstrated in the first week of life. Prematurity up to 30 weeks gestational age did not influence the results. There were only small variations in the responses from day to day, no sex differences, and no differences between infants who were small for gestational age of appropriate weight.

Antibodies to cytomegalovirus among personnel at a children's hospital.

Among 161 individual personnel at Children's Hospital, serum complement fixing antibodies were found more frequently (77%) in those who were in close contact with the patients than (39%) in those with less contact. This difference was most pronounced in the young age group. Most (80%) of the personnel at an age of 30 years or older, were seropositive, The results indicate that young personnel, working in close contact with infants and children in hospital, are at great risk of acquring cytomegalovirus infection.