Publications by authors named "E Berkowitz"
Systemic lupus erythematosus (SLE), commonly referred to as lupus, is a widely prevalent chronic autoimmune disease that can affect any organ system in the body. Although the pathogenesis of this disease is rather complex and poorly understood, ultimately there is an overproduction of multiple self-reactive antinuclear antibodies. These autoantibodies are one of the laboratory hallmarks of the diagnosis and disease activity of SLE.
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- The study investigates how the war in Israel has affected physical and mental health among 50 endometriosis patients at Sheba Medical Center through a questionnaire-based approach.
- Results showed a significant decline in both physical (pain scores increased) and mental health after the war began, with more severe effects observed in those with family involvement in the conflict.
- Starting new anti-anxiety or antidepressant medications and engaging in psychological therapy helped protect against the negative health impacts, emphasizing the need for early mental health interventions during crises.
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- Idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) are severe lung diseases that require new treatments, prompting a study on the oral drug admilparant (BMS-986278).
- A phase 2, randomized, double-blind trial was conducted with 278 IPF patients and 125 PPF patients, who received either 30mg or 60mg of admilparant or a placebo twice daily for 26 weeks, all while allowing background treatments.
- Results showed that the 60mg dose of admilparant significantly slowed the decline in lung function compared to placebo for both IPF and PPF, with a favorable safety profile, supporting further research in phase 3
In this study, we present a method based on Monte Carlo Dropout (MCD) as Bayesian neural network (BNN) approximation for confidence-aware severity classification of lung diseases in COVID-19 patients using chest X-rays (CXRs). Trained and tested on 1208 CXRs from Hospital 1 in the USA, the model categorizes severity into four levels (i.e.
View Article and Find Full Text PDFPatients with haematologic malignancies represent one of the most common groups referred for fertility preservation before gonadotoxic oncological treatment. The aim of this systematic review and meta-analysis was to evaluate the effect of haematologic cancer on ovarian reserve and response to ovarian stimulation compared with healthy controls. A total of eight observative studies were included in the final quantitative analysis.
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