Publications by authors named "E Bennink"
In this study, we present a method that enables voxel-by-voxel comparison of in vivo imaging to immunohistochemistry (IHC) biomarkers. As a proof of concept, we investigated the spatial correlation between dynamic contrast enhanced (DCE-)CT parameters and IHC biomarkers Ki-67 (proliferation), HIF-1α (hypoxia), and CD45 (immune cells). 54 whole-mount tumor slices of 15 laryngeal and hypopharyngeal carcinomas were immunohistochemically stained and digitized.
View Article and Find Full Text PDFIntroduction: Differences in body composition in patients with COPD may have important prognostic value and may provide opportunities for patient-specific management. We investigated the relation of thoracic fat and muscle with computed tomography (CT)-measured emphysema and bronchial wall thickening.
Methods: Low-dose baseline chest CT scans from 1031 male lung cancer screening participants from one site were quantified for emphysema, bronchial wall thickening, subcutaneous fat, visceral fat and skeletal muscle.
Background: During the cochlear implantation procedure, the receiver/stimulator (R/S) part of the implant is fixated to prevent postoperative device migration, which could have an adverse effect on the position of the electrode array in the cochlea. We aim to compare the migration rates of two fixation techniques, the bony recess versus the subperiosteal tight pocket without bony sutures.
Methods And Analysis: This single-blind randomized controlled trial will recruit a total of 112 primary cochlear implantation adult patients, eligible for implantation according to the current standard of practice.
Article Synopsis
- The study aimed to assess the differences in CT perfusion (CTP) imaging protocols used by various stroke centers, with a focus on potential standardization of vendor software to create more consistent CTP images.
- Researchers analyzed data from multiple centers and an anthropomorphic phantom, revealing that although the CTP scan protocols varied significantly, the software used had a greater influence on the resulting perfusion maps.
- Standardization of the estimation process for ischemic regions improved the alignment of CTP images across different vendor software, indicating that where a stroke patient is treated can greatly affect their diagnosis.
Article Synopsis
- Locating vessel occlusions is crucial for making clinical decisions in stroke treatment, and new techniques like endovascular thrombectomy are expanding the methods for finding these occlusions.
- This study created an atlas using CT perfusion (CTP) data to identify the locations of vessel occlusions by analyzing the corresponding hypoperfused regions in 596 stroke patients.
- The atlas model showed an 86% accuracy rate for identifying occlusion locations and demonstrated good agreement with expert assessments, although individual patient differences limited its effectiveness for some vessel types.