Childhood-onset Huntignton´s disease. A rare presentation.

Introduction: Huntington's disease (HD) is a rare autosomal dominant disease caused by the expansion of CAG triplets in the gene that encodes huntingtin. There are earlier symptoms' onset in offspring due to the phenomenon of anticipation. The clinical features of childhood-onset HD, before age 10 years, differs from adult-onset form.

Teleconsultation during a pandemic. Experience of developmental pediatricians at Hospital de Pediatría "Prof. Dr. Juan P. Garrahan".

Teleconsultation is one of the components of telemedicine. Developmental pediatricians provide assessments and followup to children with developmental challenges. During the pandemic, due to movement and travel restrictions and the importance of continued care, pediatricians started working remotely with virtual consultations.

Electrophysiologic study of globus pallidus projections to the thalamic reticular nucleus.

This study was designed to explore the electrophysiological relationships between the globus pallidus (GP), the substantia nigra pars reticulata (SNr) and the thalamic reticular nucleus (TRN) in urethane-anesthetized rats. The neuronal activity of the rostral part of the TRN was recorded by microelectrodes. Single pulse electrical stimulation of the GP and SNr produced inhibition of the spontaneous activity of the majority of TRN neurons.