Publications by authors named "E Bektur"
Objectives: The aim of this study was to explore the molecular mechanism of mirtazapine with respect to energy metabolism in Streptozotocin-induced diabetic liver of rats by immunohistochemistry and Western blot.
Materials And Methods: Twenty-one male Sprague-Dawley rats were assigned into 3 groups including control, type 1 diabetes mellitus (T1DM) group (55 mg/kg Streptozocin, IP) and T1DM+mirtazapine (20 mg/kg,PO) group. At the end of the experiment, blood glucose levels were measured and liver tissues were stained by Periodic acid-Schiff.
HYPOTHYROIDISM INCREASES EXPRESSION OF STERILE INFLAMMATION PROTEINS IN RAT HEART TISSUE.
Acta Endocrinol (Buchar)
January 2019
Purpose: In this study, we aimed to investigate the relationship between hypothyroidism and sterile inflammation in rat heart tissue.
Methods: Groups; control group (fed with standard rat chow diet and tab water) and the hypothyroid group (fed with a standard rat chow diet and tap water containing 0.05% 6-n-propyl-2-thiouracil for 6-weeks).
Article Synopsis
- Doctors want to help people with diabetes who have painful nerve problems, and they usually try different medicines like antidepressants and creams to relieve their pain.
- Since many patients don’t feel better with current treatments, scientists are searching for new drugs, like mirtazapine (MRT), that could work better.
- In tests on rats with diabetes, MRT helped reduce their pain and lower certain harmful levels in their body, showing that it might be a good option for treating this type of pain in people with diabetes.
Aim: The aim of this study was to investigate the effects of mirtazapine, which is anti-oxidative and antidepressant agent, on the kidney damage caused by diabetes mellitus.
Materials And Methods: The rats were randomly divided into three groups (n = 7 animals in each group). The group I rats served as control and they received 0.
Our study focuses on characterization of dorsal root ganglion (DRG) neurons cultured on silicon micro-pillar substrates (MPS) with the ultimate goal of designing micro-electrode arrays (MEAs) for successful electrophysiological recordings of DRG neurons. Adult and neonatal DRG neurons were cultured on MPS and glass coverslips for 7 days in vitro. DRG neuronal distribution and morphometric analysis, including neurite alignment and length, was performed on MPS areas with different pillar width and spacing.
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