Marking prosodic prominence for voice assistant and human addressees.

Prosodic prominence (realized with phonetic features such as increased intensity, duration, and pitch, among others) is thought to guide listeners' attention by focusing new information. This study investigates production and perception of prosodic prominence toward two types of addressees: a human and a voice assistant interlocutor. We examine how the language system adapts to this increasingly common technology, by testing whether prosodic prominence is subject to when addressing an interlocutor that is consistently rated as having less communicative ability.

is a novel allele of the gene ( ) in .

Genetic screens in have long been used to identify genes found in a variety of developmental, cellular, and behavioral processes. Here we describe the characterization and mapping of a mutation identified in a conditional screen for genetic regulators of cell growth and cell division. Within a Flp/FRT system, mutant results in a reduction of mutant tissue and a rough eye phenotype.

δC and δN zooplankton isoscapes as trace of water masses and mesoscale activity in the Pacific Tropical-Subtropical Convergence off Mexico during June 2010.

This research analyzes for the first time in the Pacific Tropical-Subtropical Convergence off Mexico during June 2010 the relationships among the δC and δN signal distribution in the bulk zooplankton, water masses, and mesoscale structures. The environmental analysis showed that the California Current Water (CCW) and Transitional Water (TrW) converge where the 22 °C isotherm and 34.6 g kg isohaline were observed (22°N).

Voltage-Gated Proton Channel Hv1 Regulates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson's Disease Models.

Although the precise mechanisms for neurodegeneration in Parkinson's disease (PD) are unknown, evidence suggests that neuroinflammation is a critical factor in the pathogenic process. Here, we sought to determine whether the voltage-gated proton channel, Hv1 (HVCN1), which is expressed in microglia and regulates NADPH oxidase, is associated with dopaminergic neurodegeneration. We utilized data mining to evaluate the mRNA expression of in the brains of PD patients and controls and uncovered increased expression of the gene encoding Hv1, in the brains of PD patients compared to controls, specifically in male PD patients.

Do disfluencies increase with age? Evidence from a sequential corpus study of disfluencies.

Speech disfluencies such as repeated words and pauses provide information about the cognitive systems underlying speech production. Understanding whether older age leads to changes in speech fluency can therefore help characterize the robustness of these systems over the life span. Older adults have been assumed to be more disfluent, but current evidence is minimal and contradictory.