Genetically engineered T cells to target EGFRvIII expressing glioblastoma.

Glioblastoma remains a significant therapeutic challenge, warranting further investigation of novel therapies. We describe an immunotherapeutic strategy to treat glioblastoma based on adoptive transfer of genetically modified T-lymphocytes (T cells) redirected to kill EGFRvIII expressing gliomas. We constructed a chimeric immune receptor (CIR) specific to EGFRvIII, (MR1-zeta).

Determination of iodine-131 at low levels in milk: collaborative study.

The official method for the determination of iodine-131 in milk has a lower limit of detection (LLD) of 10 pCi/L (0.37 Bq/L). The Nuclear Regulatory Commission had recommended that a method claiming to have an LLD of <0.

Radionuclides in domestic and imported foods in the United States, 1987-1992.

Findings from the U.S. Food and Drug Administration's Radionuclides in Foods program are summarized for foods collected between October 1, 1986, and September 30, 1992.