Publications by authors named "E Bander"

Article Synopsis
  • - Papillary craniopharyngioma (PCP) is a rare, benign tumor that accounts for about 20% of craniopharyngioma cases, primarily affecting adults and linked with the hypothalamus, presenting challenges in both diagnosis and surgical treatment due to its location.
  • - Symptoms often involve visual deficits and psychiatric issues in about 45% of patients, with MRI being effective for detection but finding only half of the cases; surgical approaches vary, with endoscopic endonasal techniques offering better outcomes.
  • - Most PCPs have the BRAFV600E mutation, which activates a key cellular signaling pathway, suggesting they may respond positively to targeted therapies like BRAF/MEK inhibitors, as shown in a recent
View Article and Find Full Text PDF
Article Synopsis
  • Fibromuscular dysplasia (FMD) is a rare condition mostly affecting women, characterized by various arterial problems that can lead to serious health issues like hypertension and stroke.* -
  • This study used genetic data from FMD patients and healthy controls to identify 18 gene regulatory networks, with four forming an FMD-related supernetwork affecting arterial health.* -
  • By disrupting this supernetwork in mice, researchers observed symptoms of FMD, revealing insights into the disease's mechanisms and potential new treatment options.*
View Article and Find Full Text PDF

Cerebrospinal fluid (CSF) leaks may occur at the skull base or along the spinal column and can cause a variety of debilitating neurological symptoms for patients. Recognizing the potential presence of a CSF leak and then identifying its source are necessary for accurate diagnosis and definitive treatment. A standardized workflow can be followed for successful leak localization, which often requires several diagnostic studies, and for definitive leak treatment, which can range from minimally invasive, needle-based approaches to a variety of surgical corrections.

View Article and Find Full Text PDF

Objective: Olfactory groove meningiomas (OGMs) often require surgical removal. The introduction of recent keyhole approaches raises the question of whether these tumors may be better treated through a smaller cranial opening. One such approach, the supraorbital keyhole craniotomy, has never been compared with more traditional open transcranial approaches with regard to outcome.

View Article and Find Full Text PDF

Importance: Adjuvant stereotactic radiosurgery (SRS) enhances the local control of resected brain metastases (BrM). However, the risks of local failure (LF) and potential for posttreatment adverse radiation effects (PTRE) after early postoperative adjuvant SRS have not yet been established.

Objective: To evaluate whether adjuvant SRS delivered within a median of 14 days after surgery is associated with improved LF without a concomitant increase in PTRE.

View Article and Find Full Text PDF