Joint Committee on Aviation Pathology: XVI. Studies on the relation between carboxyhemoglobin concentration and toxicity.

A study was made on the effect of I.P. injection of 100% CO in dogs.

Mechanism of the toxic action of carbon monoxide.

Our studies indicate that a high concentration of carboxyhemoglobin (COHb) does not interfere with the O2--carrying capacity of the blood. In dogs, both the transfusion of erythrocytes containing 80 percent COHb and the i.p.