Publications by authors named "E BECKER"
Autosomal-recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an early-onset neurodegenerative disease caused by mutations in the SACS gene. The first two mutations were identified in French Canadian populations 20 years ago. The disease is now known as one of the most frequent recessive ataxias worldwide.
View Article and Find Full Text PDFThe relationship between callous-unemotional traits and internalizing psychopathology in adolescent psychiatric inpatients: a network analysis.
Child Adolesc Psychiatry Ment Health
December 2024
Background: Numerous studies have investigated the relevance of callous-unemotional traits in relation to externalizing psychopathology among children and adolescents. However, less research has examined the connections between callous-unemotional traits and internalizing psychopathology and findings were inconsistent. Consequently, the present study aimed to elucidate the role of callous-unemotional traits in the context of depression and anxiety while controlling for conduct problems, age, and gender.
View Article and Find Full Text PDFGeneric and queryable data integration schema for transcriptomics and epigenomics studies.
Comput Struct Biotechnol J
December 2024
The expansion of multi-omics datasets raises significant challenges for data integration and querying. To overcome these challenges, we developed a generic RDF-based integration schema that connects various types of differential -omics data, epigenomics, and regulatory information. This schema employs the FALDO ontology to enable querying based on genomic locations.
View Article and Find Full Text PDFArticle Synopsis
- The text discusses how transferring DNA from organelles to the nucleus is crucial for the evolution of eukaryotes, highlighted by a study that identified a specific gene (BSTR) linked to photosynthesis in Populus trichocarpa.
- BSTR has three exons, with two derived from endophytic sources and one including a large part of a plastid gene related to Rubisco, which is essential for photosynthesis.
- Overexpressing BSTR in poplar and Arabidopsis plants led to significant increases in plant height (up to 200%) and biomass (up to 200%), demonstrating its potential for enhancing growth under field conditions.
I can't feel your face: callous-unemotional traits, social anxiety, and approach-avoidance behaviour in conduct disorder.
Child Adolesc Psychiatry Ment Health
November 2024
Article Synopsis
- The study investigates interpersonal behavior in children and adolescents with conduct disorder by examining both explicit and implicit interactions in a virtual reality setting.
- Results show that while typically developing children modify their personal space based on the emotional expressions of virtual peers, those with conduct disorder do not demonstrate this adaptive behavior.
- The lack of adjustment in interpersonal distance among conduct disorder patients is linked to heightened callous-unemotional traits and social anxiety.