[Long-term neurological outcomes in premature children with excitotoxic brain damage].

Objective: To establish the prognostic significance of a biomarker of excitotoxic brain damage (antibodies to the NR2 subunit of the N-methyl-D-aspartate (NMDA) glutamate receptor) as a predictor of damage to the central nervous system (CNS) in preterm infants.

Material And Methods: 24 newborns with a gestational age of 24-33 weeks were examined with the determination of the level of antibodies to the NR2 subunit of the NMDA glutamate receptor on the 21st day of life.

Results: In the course of the study, it was found that the level of antibodies to the NR2 subunit of the NMDA glutamate receptor on the 21st day of life, in combination with the level of cord blood lactate and the resistance of cerebral vessels on the 1st day of life, can be predictors of CNS damage in a premature baby at the age of 1 month of corrected age.

[Shear wave elastography: possibilities of the differential diagnosis of focal and diffuse changes in various organs and tissues].

Ultrasound study (USS) using a shear wave elastography procedure was made in different groups of patients with morphologically verified focal and diffuse abnormalities of both superficial organs and structures and viscera. The qualitative and quantitative characteristics of the stiffness of normal and pathologic organs and tissues were estimated; there was a significance importance of differences in benign and malignant lesions. The magnitude of fibrous changes in the hepatic parenchyma was first estimated by a USS technique; there was evidence that there were significant differences in indicators in health and various liver abnormalities.