Publications by authors named "E B Mendelson"
Article Synopsis
- The herpes simplex viruses, HSV-1 and HSV-2, are common globally and currently have no definitive cure, prompting an analysis of their distinct characteristics based on various factors such as gender, age, and health conditions.
- A study was conducted using data from the Israeli Central Virology Laboratory between 2011 and 2018, where 9189 samples were diagnosed, alongside a detailed medical data extraction from 287 females with genital infections.
- Findings revealed that HSV-2 infections were more prevalent in females and that pregnancy is a significant risk factor for reactivation of HSV-2, with a higher incidence found in women diagnosed with HSV-2 compared to those with HSV-1.
Background: Similarly to wild poliovirus, vaccine-derived poliovirus (VDPV) strains can cause acute flaccid paralysis, posing a considerable challenge to public health and the eradication of poliovirus. VDPV outbreaks, particularly VDPV type 2 (VDPV2), are increasing worldwide, including in high-income countries with high vaccine coverage. We aimed to conduct a comprehensive analysis of the molecular epidemiology of a widespread VDPV2 outbreak in Israel in 2022-23 using conventional polio identification techniques and whole-genome sequencing.
View Article and Find Full Text PDFGrounded in communication models of cultural competence, this study reports on the development and testing of the first module in a larger virtual reality (VR) implicit bias training for physicians to help them better: (a) recognize implicit bias and its effects on communication, patients, and patient care; (b) identify their own implicit biases and exercise strategies for managing them; and (c) learn and practice communicating with BIPOC patients in a culture-centered manner that demonstrates respect and builds trust. Led by communication faculty, a large, interdisciplinary team of researchers, clinicians, and engineers developed the first module tested herein focused on training goal (a). Within the module, participants observe five scenes between patient Marilyn Hayes (a Black woman) and Dr.
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- - The study investigated virological failure (VF) in HIV-1 patients on first-line antiretroviral therapy (ART) from 2010 to 2018, following 1130 individuals for a median of two years to identify contributing factors.
- - Results showed that VF occurred in 5.8% of participants, with higher risks associated with being diagnosed at CD4 counts below 200 cells/mm³ (especially with AIDS-defining conditions) and using non-integrase strand transfer inhibitor (non-INSTI) regimens.
- - The study suggests that early detection of HIV-1 and the use of INSTI-based treatments could help reduce the risk of virological failure.