Publications by authors named "E B Lamback"
Pituitary tumours (PT) are formed in the pituitary gland, a small gland situated at the base of the brain. These tumours can be categorized according to their histological origin and hormone production. In surgical series, non-functioning PT are the commonest subtype, followed by functioning somatotroph and corticotroph tumours.
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- Pituitary gigantism is a rare condition in kids caused by excessive growth hormone, often linked to genetic factors, particularly mutations in the aryl hydrocarbon receptor-interacting protein gene.
- A case study of an 11-year-old boy highlighted symptoms like progressive vision loss, rapid growth, and weight gain, with tests confirming high levels of growth hormone and indicating a tumor causing these issues.
- Despite two surgeries and medications, including Pasireotide and cabergoline, his condition showed only partial improvement, and researchers identified a new likely pathogenic genetic variant contributing to his gigantism.
Neurocytomas are neuronal tumors that are usually intraventricular. Rare cases can arise from extraventricular sites. To our knowledge, only 29 cases of extraventricular neurocytoma of the sellar region (EVNSR) have been reported in the literature.
View Article and Find Full Text PDFSomatic pathogenic variants have been shown to predict a malignant phenotype in neuroendocrine tumors. They were recently identified in aggressive pituitary tumors and carcinomas, mainly of corticotrophic origin. To our knowledge, these tumors are rare in a general cohort of pituitary tumors, with no cases described in null cell tumors.
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