[Diaskintest for tuberculosis in children and adolescents].

To study whether Diaskintest might be used as a criterion for the activity of local tuberculous changes in children and adolescents, the authors examined three groups of patients aged 0 to 17 years: 1) 20 patients with new-onset tuberculosis in the progression phase; 2) 25 patients with new-onset tuberculosis in the regression phase with the signs of consolidation and calcification; 3) 18 tuberculosis dispensary Group IIIB patients who received the basic course of therapy and had residual posttuberculous changes as calcinates and compact foci. Group 3 was found to greatly differ from Groups 1 and 2 in the lower rates of positive reactions, the higher rate of negative reactions, and smaller papulae while the Mantoux test with 2 TE indicated that in Group 3, the papulae were smaller than those in Group 2. Responses to the Diaskintest test versus the Mantoux 2TE test were significantly more pronounced in patients with progressive tuberculosis and less marked in dispensary Group IIB patients who received the basic course of antituberculous therapy.

[Structural and thermodynasmic aspects of the packing of collagen fibrils].

Studies devoted to the analysis of the mechanisms of packing of collagen fibrils and the effect of the macromolecular structure and the physicochemical parameters of medium on the packing are reviewed.

[Total protein and RNA biosynthesis in the liver cells of the long-tailed suslik Citellus undulatus in different functional states].

The synthesis of proteins and RNA have been studied by means of labeled precursors of 14C-amino acids and 14C-orotic acid in liver cells of hibernating, arousing and active ground squirrels (Citellus undulatus). The investigations conducted testify to the possibility of CHI-inhibited synthesis of proteins in liver cells of hibernating ground squirrels, which occurs, apparently, on preexisting polyribosomes. The low level of protein biosynthesis in this state is stipulated not only by the Arrhenius dependence, but by the dissociation of polyribosomes into monosomes as well.