Comparison of dopamine release and uptake parameters across sex, species and striatal subregions.

For over four decades, fast-scan cyclic voltammetry (FSCV) has been used to selectively measure neurotransmitters such as dopamine (DA) with high spatial and temporal resolution, providing detailed information about the regulation of DA in the extracellular space. FSCV is an optimal method for determining concentrations of stimulus-evoked DA in brain tissue. When modelling diseases involving disturbances in DA transmission, preclinical rodent models are especially useful because of the availability of specialized tools and techniques that serve as a foundation for translational research.

Inositol Restores Appropriate Steroidogenesis in PCOS Ovaries Both In Vitro and In Vivo Experimental Mouse Models.

Androgen excess is a key feature of several clinical phenotypes of polycystic ovary syndrome (PCOS). However, the presence of FSH receptor (FSHR) and aromatase (CYP19A1) activity responses to physiological endocrine stimuli play a critical role in the pathogenesis of PCOS. Preliminary data suggest that myo-Inositol (myo-Ins) and D-Chiro-Inositol (D-Chiro-Ins) may reactivate CYP19A1 activity.

Interaction Networks Help to Infer the Vulnerability of the Saproxylic Beetle Communities That Inhabit Tree Hollows in Mediterranean Forests.

Insect communities are facing contrasting responses due to global change. However, knowledge on impacts of communities' reorganizations is scarce. Network approaches could help to envision community changes in different environmental scenarios.

Idiopathic Intracranial Hypertension: An Unusual Cause of Headache in a Patient With Sickle Cell Disease.

Idiopathic intracranial hypertension (IIH) is a rare cause of headache and visual disturbance with no known association with sickle cell disease (SCD). We present a patient with SCD with gradual onset of a severe headache and visual changes. Brain magnetic resonance imaging, angiography, and venography were nondiagnostic.

Sex specificity of dispersal behaviour and flight morphology varies among tree hollow beetle species.

Background: Flight performance and dispersal behaviour can differ between sexes, resulting in sex-biased dispersal. The primary sex ratio of populations may also explain dispersal bias between sexes, as this bias may evolve with the primary sex ratio to reduce intrasexual competition. Although dispersal bias between sexes is relevant to population dynamics, there are few studies on sex-biased dispersal in insects.