AI in Point-of-Care - A Sustainable Healthcare Revolution at the Edge.

This paper examines the integration of artificial intelligence (AI) in point-of-care testing (POCT) to enhance diagnostic speed, accuracy, and accessibility, particularly in underserved regions. AI-driven POCT is shown to optimize clinical decision-making, reduce diagnostic times, and offer personalized healthcare solutions, with applications in genome sequencing and infectious disease management. The paper highlights the environmental challenges of AI, including high energy consumption and electronic waste, and proposes solutions such as energy-efficient algorithms and edge computing.

Earth Friendly Computation: Applying Indigenous Data Lifecycles in Medical and Sovereign AI.

The following sections are included: Overview, Background & key terms, Earth Friendly Computation 574: Indigenous Data Sovereignty, Circular Systems, and Solarpunk Solutions for a Sustainable Future, AI in Point-of-Care: A Sustainable Healthcare Revolution at the Edge, Conclusion: The Future of Earth Friendly Computation, Acknowledgments, References.

Navigating the coronavirus pandemic two years on: Experiences of carers of people with dementia from the British IDEAL cohort.

We explored carers experiences during the COVID-19 pandemic in England to identify long-term impacts and implications, and to suggest future support for caregivers. Data were collected during COVID-19 rapid response studies (IDEAL-CDI; INCLUDE) from carers participating in a British longitudinal cohort study (IDEAL). Semi-structured interview data were compared to their accounts from previous interviews conducted during the first 18 months of the pandemic.

Analytical Performance of a Multiplexed Microarray Assay for Rapid Identification and Quantification of a Multivalent mRNA Vaccine.

mRNA vaccines were highly effective in response to the COVID-19 pandemic, making them an attractive platform to address cancers and other infectious diseases. Many new mRNA vaccines in development are multivalent, which represents a difficulty for the standard assays commonly used to characterize the critical quality attributes of monovalent formulations. Here, we present a multiplexed analytical tool with nucleic acid microarray technology using the VaxArray platform that measures the identity and quantity of mono- and multivalent mixtures of naked mRNA and mRNA encapsulated in lipid nanoparticle formulations in under 2 h without any additional preparation steps, such as extraction or RT-PCR.

In vitro gametogenesis (IVG): reflections from a workshop.

Key ideas from a workshop convened by the National Academies of Sciences, Engineering, and Medicine to discuss developments in IVG (National Academies of Sciences, Engineering, and Medicine 2023) chaired by Dr Eli Y. Adashi (former Dean of Medicine and Biological Sciences at Brown University). The authors are solely responsible for the content of this paper, which does not necessarily represent the views of the National Academies of Sciences, Engineering, and Medicine.