An In Vivo High-Resolution Human Brain Atlas of Synaptic Density.

Synapses are fundamental to the function of the central nervous system and are implicated in a number of brain disorders. Despite their pivotal role, a comprehensive imaging resource detailing the distribution of synapses in the human brain has been lacking until now. Here, we employ high-resolution PET neuroimaging in healthy humans (17F/16M) to create a 3D atlas of the synaptic marker Synaptic Vesicle glycoprotein 2A (SV2A).

Muscle strength and endurance after surgery for primary hyperparathyroidism.

Objective: To evaluate the effect of surgery on muscular strength and endurance in patients with primary hyperparathyroidism (HPT).

Design: Prospective open study.

Setting: University hospital, Sweden.

Effects of detraining following short term resistance training on eccentric and concentric muscle strength.

Healthy males were examined before and after 12 weeks of accommodated resistance training (three week-1) and after 12 weeks of detraining. Training consisted of four to five sets of six coupled maximum voluntary bilateral concentric and eccentric (Grp ECCON; n = 10) or 12 concentric (Grp CON; n = 8) quadriceps muscle actions. Concentric and eccentric peak torque at various constant angular velocities and three repetition maximum half-squat and vertical jump height were measured.

Responses to eccentric and concentric resistance training in females and males.

The adaptive responses to 12 weeks of accommodated resistance training were compared in females (n = 11) and males (n = 11). They performed four to five sets of six maximum bilateral coupled concentric and eccentric quadriceps muscle actions at 1.05 rad s-1 three times per week.

Effects of eccentric and concentric resistance training on skeletal muscle substrates, enzyme activities and capillary supply.

This study compared the skeletal muscle metabolic adaptations in response to combined eccentric and concentric or concentric resistance training regimens. Twenty-six physically active males were assigned to either the combined eccentric and concentric group (n = 10), the concentric group (n = 10) or the control group (n = 6). The combined eccentric and concentric and the concentric groups performed four to five sets of maximal, voluntary bilateral quadriceps muscle actions at 1.