Publications by authors named "E B Brennan"
Background: Diabetic heart disease may eventually lead to heart failure, a leading cause of mortality in diabetic individuals. The lack of effective treatments for diabetes-induced heart failure may result from a failure to address the underlying pathological processes, including chronic, low-grade inflammation. Previous studies have reported that lipoxin A (LXA), known to promote resolution of inflammation, attenuates diabetes-induced atherosclerosis, but its impact on diabetic hearts has not been sought.
View Article and Find Full Text PDFBackground: This study systematically reviews the literature and reports on outcomes of total ankle arthroplasty (TAA) with the INBONE II fixed-bearing implant.
Methods: PubMed, SCOPUS and CINAHL were searched for clinical studies reporting INBONE II specific outcomes from database inception through July 13th, 2024, according to the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) guidelines.
Results: Seven primary TAA studies and 4 revision TAA studies were included with 406 and 114 patients respectively.
Article Synopsis
- Many Australian adults who smoke mistakenly believe that reducing their cigarette intake effectively lowers health risks associated with smoking.
- A significant portion of smokers, particularly those smoking less frequently, underestimate the dangers of smoking just one cigarette per day.
- The study highlights a widespread misunderstanding surrounding the effectiveness of cutting down on smoking, which emphasizes the need for better education regarding the risks involved with any level of tobacco consumption.
Article Synopsis
- The study examines disparities in healthcare related to race, ethnicity, and socioeconomic status during perioperative anesthetic management for patients undergoing coronary artery bypass grafting (CABG).
- It analyzed data from 1404 adult CABG patients between 2017 and 2022, focusing on outcomes like postoperative nausea and vomiting (PONV) and pain, alongside various independent variables such as race and healthcare payer types.
- Results showed no significant disparities in the management of pain or PONV across different racial or socioeconomic groups, highlighting the importance of applying a health equity lens to ensure fair treatment during surgery.
Fungal dysbiosis following antibacterial monotherapy in canine otitis externa.
J Small Anim Pract
November 2024
Article Synopsis
- The study aimed to investigate whether treating refractory bacterial otitis in dogs with specific topical antibiotics leads to an increase in yeast overgrowth, particularly Malassezia.
- Twenty-nine dogs were treated with either fluoroquinolone or a combination of piperacillin and tazobactam, and ear swabs were taken to measure bacterial and yeast levels before and after treatment.
- Results showed a significant reduction in bacterial infections after treatment, but a notable increase in yeast (especially in dogs treated with piperacillin/tazobactam), highlighting the importance of monitoring for yeast overgrowth during antibacterial treatment.