Publications by authors named "E Ayas"

Article Synopsis
  • The MONALEESA-7 study is the only phase 3 research on CDK 4-6 inhibitors for premenopausal patients with hormone receptor-positive, HER2 negative metastatic breast cancer, but there is limited data on palbociclib's effectiveness.
  • Our multicenter, retrospective study included 319 patients to evaluate the effectiveness of palbociclib and ribociclib in first-line treatment and how dose reduction due to neutropenia affects progression-free survival (PFS).
  • Results showed similar median PFS for both drugs (26.83 months for palbociclib and 29.86 months for ribociclib) and no significant impact of dose reduction on effectiveness, with P
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α-β SiAlON/TiN composites with nominal composition of α:β = 25:75 were fabricated by microwave sintering. The effect of titanium nitride addition on the phases, microstructure, microwave absorption ability and mechanical properties (Vickers hardness and fracture toughness) of the SiAlON-based composites were studied. Finite Difference Time Domain (FDTD) software was used for the numerical simulation in order to assess the most suitable experimental setup.

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