Publications by authors named "E Auclin"
Article Synopsis
- This systematic review investigates the effects of sex on treatment outcomes in patients with non-small cell lung cancer (NSCLC) who have specific gene fusions and are treated with targeted therapies.
- The review analyzed data from 10 studies focusing on progression-free survival (PFS) and 3 studies examining overall survival (OS), finding no significant differences in survival between male and female patients receiving ALK inhibitors.
- The lack of available data regarding sex-based differences in response rates and adverse events highlights a critical gap in understanding how sex may influence treatment effectiveness and safety in targeted therapy for NSCLC.
Association of Lung Immune Prognostic Index (LIPI) with Disease Control Rate and Progression-Free Survival in Patients with Soft-Tissue Sarcoma Treated with Immunotherapy in Early-Phase Trials.
Cancers (Basel)
December 2024
Background: The efficacy of immunotherapies in soft-tissue sarcomas (STSs) is limited, and biomarkers of response are lacking. The lung immune prognostic index (LIPI) is a prognostic biomarker used with immunotherapy across cancer types. This study investigates the association of LIPI with the disease control rate (DCR) and progression-free survival (PFS) in patients with STS treated with immunotherapy versus other therapies in early-phase trials.
View Article and Find Full Text PDFIntroduction: LIPI has been strongly correlated with immunotherapy (IT) outcomes in advanced NSCLC. Limited data is available for upfront chemotherapy (CT) + IT combinations. We aimed to study its prognostic value in 1st-line CT +/- IT +/- antiangiogenics.
View Article and Find Full Text PDFBackground: Limited data are available on long-term respiratory disabilities in patients following acute COVID-19.
Patients And Methods: This prospective, monocentric, observational cohort study included patients admitted to our hospital with acute COVID-19 between 12 March and 24 April 2020. Clinical, functional and radiological data were collected up to 28 months after hospital discharge.
Introduction: General Practitioners (GPs) play a key role of gatekeeper, as they coordinate patients' care. However, most of them reported having difficulty to refer patients to hospital, especially in semi-urgent context. To facilitate the referral of semi-urgent patients, we implemented an e-referral platform, named SIPILINK, within 4 wards from a large public French hospital (internal medicine, diabetology, gynaecological surgery and oncology wards).
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