Publications by authors named "E Anastasopoulou"

Introduction: Wearable Activity Trackers (WATs) offer real-time feedback on activity levels. We assessed the impact of WAT usage on physicians' exercise habits.

Methods: Physicians from the Athens Medical Association, Greece (n = 742) responded to a self-administered questionnaire evaluating usage of WAT, demographic characteristics, specialty, and physical exercise habits.

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Article Synopsis
  • The study aimed to gather real-world data on the EGFR mutational profile and treatment strategies for advanced non-small-cell lung cancer (NSCLC) patients after first/second-generation EGFR-TKI treatment.
  • Ninety-six patients were enrolled in Greece, with re-biopsies conducted for some who were negative for the T790M mutation.
  • Results showed that 21.9% of patients were T790M-positive, and those receiving third-generation EGFR-TKIs had better outcomes, highlighting the importance of mutational status and treatment choices in improving response rates and progression-free survival.
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To retrospectively characterize real-world therapeutic strategies, clinical outcomes and attrition rates with EGFR tyrosine kinase inhibitors (TKIs), before first-line osimertinib approval, in -mutated advanced/metastatic non-small-cell lung cancer patients in Greece. Among 160 patients, the discontinuation rate for first-line first- or second-generation EGFR-TKIs was 85%; among these patients, 43% did not receive any second-line therapy and 9.4% died during an 18.

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Purpose: AE37 and GP2 are HER2 derived peptide vaccines. AE37 primarily elicits a CD4+ response while GP2 elicits a CD8+ response against the HER2 antigen. These peptides were tested in a large randomized trial to assess their ability to prevent recurrence in HER2 expressing breast cancer patients.

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The essential oil of Pimpinella anisum L. (Apiaceae) seeds from Lesvos Island (Greece), famous as flavor for the production of the aperitif "ouzo", has been analyzed by GC-MS for the first time. Additionally, three samples of the Greek market originated from North and Central Greece (Thessaly, Viotia) and Turkey, were also analyzed and all of them were compared to the quality limits given in European Pharmacopoeia for medicinal purposes.

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