Publications by authors named "E Altinoz"
Article Synopsis
- Chronic obstructive pulmonary disease (COPD) is a major global health issue, and factors like biomass exposure, patient demographics, and other health conditions play a significant role in worsening patient outcomes during episodes of exacerbation.
- A study analyzed medical records of 334 COPD patients from January 2021 to December 2023, focusing on how biomass exposure influences hospital outcomes like ICU admissions, length of stay, and in-hospital mortality, rather than looking at its direct effects.
- Results showed that patients with biomass exposure were more likely to be female, had lower smoking rates, and experienced higher ICU admissions and mortality; older patients also faced greater health challenges during their hospital stays, although specific characteristics didn't significantly correlate with outcomes.
The study aimed to determine the CCl-induced liver fibrosis model in pinealectomized rats and biochemically, immunohistochemically, and histopathologically investigate the therapeutic effect of melatonin on liver fibrosis. The surgical procedure for pinealectomy was performed at the beginning of the study, and the sham and pinealectomized rats were administered CCl dissolved in corn oil (1:1) alone every other day to induce liver fibrosis or together with melatonin (10 mg/kg) therapy for 15 days. Melatonin is an essential therapeutic agent and offers an alternative therapeutic strategy in CCl-induced liver fibrosis by suppressing inflammation, oxidative stress, and the TGF-β1 signaling pathway.
View Article and Find Full Text PDFDoxorubicin (Dox), an anthracycline antibiotic, is a chemotherapeutic drug for several cancer treatments. However, its clinical usage has been restricted because of severe side effects, including nephrotoxicity. This study aimed to demonstrate the possible nephroprotective effects of crocin (Cr) against Dox-induced oxidative stress, renal inflammation, renal morphology and transforming growth factor-β (TGF-β) signalling pathways in Dox-exposed rats.
View Article and Find Full Text PDFObjective: Acrylamide (AA) is toxic and forms in food that undergoes high-temperature processing. This study aimed to investigate the effects of AA-induced toxicity on renal tissue in pinealectomized rats and the possible protective effect of exogenous Melatonin (ML) administration.
Materials And Methods: Sixty rats were randomized into 6 groups (n = 10): Sham, Sham+AA, Sham+AA+ML, PX, PX+AA, and PX+AA+ML.
The Effect of Intracochlear and Intratympanic Dexamethasone on Cochlear Implant Impedance.
Turk Arch Otorhinolaryngol
September 2023
Objective: This study investigated the impact of different local corticosteroid applications on impedance measurements in patients with cochlear implants.
Methods: The study was designed as a controlled, randomized, and prospective study in which 34 consecutive patients who had undergone cochlear implant surgery were divided into three groups. The first group received intracochlear dexamethasone, in the second group the middle ear cavity was filled with dexamethasone, and the third group did not receive dexamethasone.