Safety and efficacy of unpreserved timolol 0.1% gel in patients controlled by preserved latanoprost with signs of ocular intolerance.

Purpose: To assess the safety and efficacy of unpreserved timolol 0.1% gel in ocular hypertensive (OHT) or glaucomatous patients controlled by preserved latanoprost 0.005% but with signs of ocular intolerance.

Responses of a Mediterranean soft bottom community to short-term (1993-1996) hydrological changes in the Rhone river.

The polychaete fauna of muddy bottoms off the Rhone delta (NW Mediterranean) was seasonally sampled at two sites at 70 m depth, from 1993 to 1996. During this period, five severe flood events occurred. A clustering analysis (distance coefficient of Whittaker) and three way fixed factor ANOVAs (site x season x year) showed strong year-to-year changes in species density and community structure, changes that masked seasonal variations.

Toxicity of French strains of the dinoflagellate Prorocentrum minimum experimental and natural contaminations of mussels.

Mediterranean strains of Prorocentrum minimum do not appear to have the same toxic component as Japanese strains since they showed no cytotoxicity for hepatocytes in culture. However, their toxic components, which appear to block calcium channels, were detectable by the immobilisation test on Diptera larvae. A bio-accumulation experiment in the laboratory showed that the toxins could accumulate in nearly equivalent amounts in the hepatopancreas and meat of cultured mussels.

[Benign intracranial hypertension. Retrospective study of 20 cases].

Purpose: We conducted a retrospective study in 20 cases of idiopathic intracranial hypertension (IIH) referred to the ophthalmology out-patients department at the Centre Hospitalier Universitaire of Fort de France. The objectives were to characterize symptomatology, severity, disease course and to discuss treatment.

Methods: We performed a complete ophthalmological and neurological examination, calculated the body mass index (BMI) and evaluated visual field.

[Juvenile glaucoma. Seven case reports].

Background: Juvenile glaucoma is an uncommon form of chronic open angle glaucoma that appears between 3 and 35 years of age.

Methods: We report in this study seven cases of juvenile glaucoma that occurred in patients melanoderma.

Results: Three of them had unilateral blindness and in two others visual acuity was reduced to light perception in one eye.