Publications by authors named "E Akokuwebe Monica"

Herein, we investigated the toxicity and membrane-permeabilizing capabilities of Lpt and Lpt-like peptides, belonging to type I toxin-antitoxin systems carried by plasmid DNA of strains. These 29 amino acid peptides are predicted to form α-helical structures with a conserved central hydrophobic sequence and differently charged hydrophilic termini. Like Lpt, the expression of Lpt-like in induced growth arrest, nucleoid condensation, and cell membrane damage, suggesting membrane interaction as the mode of action.

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Article Synopsis
  • * An anonymous online survey was conducted with 728 pediatric residents and 196 teaching staff from 15 universities, assessing their familiarity with information technology (IT) and AI in child health education.
  • * Results showed that most respondents were familiar with IT and AI, believed these technologies simplified learning, and were supportive of incorporating them into educational practices.
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Male partners play a crucial role in reproductive health matters and seem to be identified as the main contributors responsible for the large proportion of poor reproductive health suffered by their female partners. Limited evidence exists, however, on effective strategies to increase male involvement in family planning. Therefore, this study aims to examine the prevalence and factors associated with male involvement in family planning decisions.

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Purpose: This systematic review and meta-analysis aimed to compare endoscopy as primary versus secondary prophylaxis to prevent future bleeding in children with esophageal varices.

Methods: A systematic literature search using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method was conducted using the Scopus, PubMed, and Cochrane databases for relevant studies on the outcome of rebleeding events after endoscopy in primary prophylaxis compared to that in secondary prophylaxis. The following keywords were used: esophageal varices, children, endoscopy, primary prophylaxis and bleeding.

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Uric acid is the main means of nitrogen excretion in uricotelic vertebrates (birds and reptiles) and the end product of purine catabolism in humans and a few other mammals. While uricase is inactivated in mammals unable to degrade urate, the presence of orthologous genes without inactivating mutations in avian and reptilian genomes is unexplained. Here we show that the Gallus gallus gene we name cysteine-rich urate oxidase (CRUOX) encodes a functional protein representing a unique case of cysteine enrichment in the evolution of vertebrate orthologous genes.

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