Publications by authors named "E Agren"

Article Synopsis
  • The study identifies two types of treponemes infecting lagomorphs: Treponema paraluisleporidarum ecovar Cuniculus (TPeC), affecting rabbits, and ecovar Lepus (TPeL), affecting hares, with a focus on the complete genome sequence of TPeL from a mountain hare in Sweden.
  • Researchers successfully sequenced nearly the entire genome of TPeL, revealing similarities and differences between TPeL and TPeC, including notable gene variations that could influence how these pathogens adapt to their hosts.
  • Phylogenetic analysis indicated that the TPeL isolate from the European brown hare is more distantly related to TPeC than the other TPeL
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Transmissible spongiform encephalopathies or prion diseases comprise diseases with different levels of contagiousness under natural conditions. The hypothesis has been raised that the chronic wasting disease (CWD) cases detected in Nordic moose () may be less contagious, or not contagious between live animals under field conditions. This study aims to investigate the epidemiology of CWD cases detected in moose in Norway, Sweden and Finland using surveillance data from 2016 to 2022.

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Factors behind intraspecific variation in sensitivity to pathogens remain poorly understood. We investigated how geographical origin in two North European amphibians affects tolerance to infection by the chytrid fungus Batrachochytrium dendrobatidis (Bd), a generalist pathogen which has caused amphibian population declines worldwide. We exposed newly metamorphosed individuals of moor frog Rana arvalis and common toad Bufo bufo from two latitudinal regions to two different BdGPL strains.

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Article Synopsis
  • Syphilis is an ancient disease caused by two closely related bacteria, with extensive research on human syphilis but limited knowledge regarding its impact on lagomorphs (like rabbits).
  • Comparative studies are necessary to understand the coevolution of hosts and pathogens, especially using hare populations that are naturally infected with the syphilis-causing bacteria.
  • This research provides new data on the genetic diversity of the bacteria, specifically highlighting variations in hypervariable regions that have not been previously documented in the human strain.
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Prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. They are characterized by the conformational conversion of the cellular prion protein (PrP) into the pathological prion protein (PrP). In 2016, chronic wasting disease (CWD) gained great importance at European level due to the first disease detection in a wild reindeer (Rangifer tarandus) in Norway.

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