Publications by authors named "E Abdollahi"
Objective: Serotonin reuptake inhibitors cause weight gain, leading to drug discontinuation, relapse, and worsening of symptoms. This study aims to investigates the effect of metformin on weight loss, anthropometric indicators and laboratory assessments in patients of Rasht city.
Methods: This clinical trial study with parallel-group design was organized based on 60 patients in treatment group (undergoing metformin) and 60 patients in control group (undergoing routine treatment) in Shafa hospital during July 2019 to January 2020.
Background: Severe mental illnesses (SMIs), including schizophrenia and bipolar disorder affect patients significantly. Gender has been identified as a key factor influencing the experience of SMIs with notable disparities in prevalence, symptoms, and treatment outcomes. Additionally, the quality of life (QoL) and social support for patients with SMIs can vary based on gender.
View Article and Find Full Text PDFBerberine is a well-known phytochemical with significant antiviral activity against a wide range of viruses. Due to having a unique backbone consisting of four interconnected rings, it can be used as a platform for the design and development of novel semisynthetic antiviral agents. The question here is whether novel broad-spectrum antiviral drugs with enhanced activity and toxicity potential can be obtained by attempting to modify the structure of this privileged lead compound.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluates the cost-effectiveness of using nirsevimab, a long-acting monoclonal antibody, and RSVpreF, a maternal vaccine, to protect infants from Respiratory Syncytial Virus (RSV) in Canada.
- A discrete-event simulation model was developed to analyze RSV infections and the health outcomes associated with different vaccination strategies over one year from birth, considering both healthcare and societal costs.
- Findings suggest that immunizing the entire birth cohort with nirsevimab is cost-effective at a price-per-dose of up to CAD$290, while a combined strategy of vaccinating pregnant women and at-risk infants also demonstrates potential benefits.
Objective: Determining cellular radiosensitivity of breast cancer (BC) patients through molecular markers before radiation therapy (RT) allows accurate prediction of individual's response to radiation. The aim of this study was therefore to investigate the potential role of epigenetic biomarkers in breast cancer cellular radiosensitivity.
Materials And Methods: In this experimental study, we treated two BC cell lines, MDA-MB 231 and MCF-7, with doses of 2, 4, and 8Gy of irradiation for 24 and 48 hours.