Publications by authors named "E A el Zayat"

The study explored the antimicrobial, antibiofilm, and hemostatic properties of chitosan microflowers (CMF) in sponge form. The main objective was to enhance the preparation of CMF by employing varying quantities of calcium chloride (CaCl) and tripolyphosphate (TPP). CMF was then combined with gelatin (GE) in different proportions to produce three sponge samples: CMF0@GE, CMF1@GE, and CMF2@GE.

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Article Synopsis
  • Cervical cancer is primarily associated with HPV types 16 and 18, and the study investigates the antiviral and anticancer potential of Tanacetum sinaicum essential oil (EO) on human cervical and breast cancer cell lines.
  • The EO was extracted and characterized, and its effects on cell viability were measured; it was found to significantly reduce the growth of cancer cells in a dose-dependent manner, with higher concentrations leading to over 95% inhibition.
  • Additionally, the EO effectively decreased HPV replication in the tested cell lines and exhibited autophagy-enhancing and genotoxic effects, suggesting its potential roles in cancer treatment.
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Skin cancer is considered a risky worldwide disease. Traditional treatments have several weaknesses, necessitating the creation of more effective treatments. In this case, photodynamic therapy and nanotechnology were used to demonstrate their therapeutic efficacy as combinational approaches in treating different types of skin cancer.

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Background: Adipose mesenchymal stem cells (AMSCs) are a type of stem cell employed to repair damaged organs. This study aimed to see how effective AMSCs are at treating gentamycin- induced hepatorenal damage in rats.

Methods: 18 male Wister rats were assigned into three groups; control, Gentamycin (GM), and GM+AMSCs.

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Purpose: Vascular targeted photodynamic therapy with WST11 (TOOKAD® Soluble) is in phase III clinical trials of an interstitial transperineal approach for focal therapy of prostate cancer. We investigated the safety and efficacy of the endourethral route in the context of benign prostatic hyperplasia in the dog model.

Materials And Methods: An optical laser fiber was positioned in the prostatic urethra of 34 dogs, including 4 controls.

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