Whole-body repeated hyperthermia increases irisin and brain-derived neurotrophic factor: A randomized controlled trial.

Context: Hyperthermia is known to be beneficial to patients affected by various diseases. Irisin is a key regulators of fat metabolism known to be released as response to cold. Brain Derived Neurotrophic Factor (BDNF) is a marker of neuroplasticity usually increased as response to acute exposure to human body stressors.

Neurophysiological method of micro sampling of endogenous substances and their transfer from one structure to another brain structure.

A fundamentally new priority method has been developed for the microsampling of endogenous substances from one brain structure for their subsequent introduction into another brain structure. The same universal capillary is first used to extract endogenous substances located in a certain brain structure, and then the same capillary is used to transfer collected substances to another brain structure by increasing the pressure in the capillary when the laser beam heats up its closed cavity located outside. The method can be used to study the neurochemical mechanisms of the formation of emotional-motivational and pathological conditions, and identify specific endogenous substances involved in these processes.

[Monitoring of human physiological functions during the daily night sleep].

The basic somnological methodology, which is extensively used in the present time, focuses only on clinical practice. However, this approach is not appropriate for monitoring of physiological functions during natural sleep under home conditions. Our work was designed to develop a new information-and-equipment device for the reliable study of human physiological functions during sleep in the real everyday life.

Long-distance effects of human subjective status on the blood physicochemical characteristics.

The external long-distance manifestations of the subjective status of a human being are analyzed. The subjective states of a human being can be objectively recorded at a long distance. A contact-free long-distance effect of human subjective status on the physicochemical parameters of the blood is demonstrated.

Stages of sleep after psychoemotional tension: the individual character of changes.

This report describes complex psychophysiological studies of nocturnal sleep in healthy humans in normal concentrations and after emotional tension. A series of contemporary methods was used: questionnaires, psychological tests, motor tests, and polysomnography with heart rate recording. These experiments showed that psychoemotional tension induced changes mainly in the structure of the first sleep cycle, decreasing the proportion of the second stage of slow sleep in total nocturnal sleep, led to a redistribution of delta sleep, increasing delta sleep in the second half of nocturnal sleep, and suppressed the mechanisms underlying the organization of the phases of rapid sleep.