Publications by authors named "E A Velasquez"
Protein phosphatases are critical for regulating cell signaling, cell cycle, and cell fate decisions, and their dysregulation leads to an array of human diseases like cancer. The dual specificity phosphatases (DUSPs) have emerged as important factors driving tumorigenesis and cancer therapy resistance. DUSP12 is a poorly characterized atypical DUSP widely conserved throughout evolution.
View Article and Find Full Text PDFThe high accumulation of plastic waste in the environment has led to great interest in biodegradable polymers, such as polylactic acid (PLA) or polyhydroxyalkanoates (PHAs). Their benefits, combined with the application of electrospinning technology, represent an innovative proposal for the food packaging industry. This article provides a comprehensive review of the latest developments of PLA- and PHA-biopolyester-based electrospun materials for food packaging applications, summarizing the reported technologies, material properties, applications, and invention patents.
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- The integration of real-world data (RWD) and machine learning (ML) enhances the understanding of complex clinical pharmacology questions by examining drug dosing regimens.
- A framework utilizing ML algorithms, applied to the drug atezolizumab, demonstrates its effectiveness, particularly using XGBoost for analyzing diverse dosing regimens.
- Initial findings indicate that factors like metastatic breast cancer and the use of protein-bound paclitaxel significantly influence the choice of the 840 mg every 2 weeks regimen, offering insights for future studies on atezolizumab and similar drugs.
Background: Emerging evidence has underscored the harmful effects of air pollution on the upper airway. We investigated the relationship between ambient particulate matter (PM) level and the frequency of outpatient visits for chronic rhinosinusitis (CRS).
Methods: We conducted an ecological cohort study of US adults enrolled in The Merative MarketScan outpatient database from 2007 to 2020.