[Etiology of bacterial endocarditis in patients with congenital heart defects].

In 90 patients with various congenital heart diseases complicated by bacterial endocarditis multiple inoculations of the blood were practised. In 14 patients microbial cultures were planted postmortem with vegetation on the endocardium, valves and also from the thrombi in the cardiac chambers and from the spleen. In 42.

[Resistance of the Staphylococcus aureus isolated from patients operated on for cardiovascular diseases to penicillins, cephalosporins and the salts of heavy metals, their lysogenicity and phagotype].

The analysis of the results obtained on the study of 55 strains of Staph. aureus isolated from purulent excretion in the patients operated under conditions of artificial blood circulation provided a conclusion that most of the clinical staphylococcal cultures were highly resistant to the beta-lactamase sensitive antibiotics. It was supposed that the above strains possessed penicillinase plasmids, since all the cultures tested had penicillinase activity and were resistant to benzylpenicillin, the resistance exceeding 1.