[Visit-to-visit blood pressure variability: clinical and prognostic significance].

The phenomenon of variability of blood pressure (BP) was studied for a long time, but recently it has received increased attention, with the focus shifted from short-term BP variability, estimated at daily monitoring for clinical blood pressure variability from visit to visit, which can be regarded as one of the indicators quality control of blood pressure with prolonged treatment. In light of the recent years of clinical data from visit to visit BP variability seems a promising new target for antihypertensive therapy.

[Salt consumption and arterial hypertension: are there reasons to change point of view?].

The review presents modern data on interrelationships between sodium consumption, blood pressure level, and risk of cardiovascular complications. Phenomenon of salt sensitivity and methods of its detection are described. Results of epidemiological and interventional studies are used as a basis for formulation of populational strategy of limitation of sodium consumption.

[Analysis of maintenance of redundant genetic structures in the yeast Saccharomyces cerevisiae: effect of mutations cdc28-srm and srm1].

The effects of nuclear gene mutations cdc28-srm and srm1 on the maintenance of various recombinant facultative genetic structures (FGSs) in Saccharomyces cerevisiae were studied. These structures are ARS1 TRP1 mini-coils, noncentromeric circular plasmids containing various ARS elements, and extended linear yeast artificial chromosomes (YAC). These mutations led to an increase in the mitotic stability of some of the FGS tested and the disturbed maintenance of the others.