Publications by authors named "E A Suvanto"

Article Synopsis
  • Research shows that women with premature ovarian insufficiency (POI) are significantly more likely to have a history of severe autoimmune diseases, occurring 2.6 times more often than those without POI.
  • The study analyzed data from nearly 4,000 women diagnosed with spontaneous POI, comparing their health outcomes to over 15,000 matched controls, which included tracking autoimmune diagnoses from childhood through 2017.
  • Findings indicate that women with POI not only had a higher prevalence of autoimmune disorders prior to their diagnosis but also faced a 2 to 3 times increased risk for these diseases for several years afterward.
View Article and Find Full Text PDF

Background: Establishing local trimester-specific reference intervals for gestational TSH and free T4 (FT4) is often not feasible, necessitating alternative strategies. We aimed to systematically quantify the diagnostic performance of standardized modifications of center-specific nonpregnancy reference intervals as compared to trimester-specific reference intervals.

Methods: We included prospective cohorts participating in the Consortium on Thyroid and Pregnancy.

View Article and Find Full Text PDF
Article Synopsis
  • * The study analyzed data from 65,559 participants across 25 cohorts, focusing on risk factors like maternal age, BMI, and antibody positivity while excluding those with pre-existing thyroid issues.
  • * Results indicated a screening rate of 58% among high-risk cohorts, with minimal variation in risk for hypothyroidism based on age and BMI, and TPOAb/TgAb positivity significantly correlated with higher risks for overt and subclinical hypothyroidism.
View Article and Find Full Text PDF

Introduction: To investigate the occurrence of previous cancer diagnoses in women suffering from premature ovarian insufficiency (POI) and compare it with the general population, shedding light on the association between cancer, cancer treatments, and POI.

Material And Methods: We conducted a nationwide case-control study based on registry data from various sources, including the Social Insurance Institution, Finnish Population Information System, and Finnish Cancer Registry spanning from 1953 to 2018. Our participants comprised all women in Finland who, between 1988 and 2017, received hormone replacement therapy reimbursement for ovarian insufficiency before the age of 40 years (n = 5221).

View Article and Find Full Text PDF
Article Synopsis
  • Triiodothyronine (T3) is important for understanding pregnancy outcomes, but its relationship with adverse obstetric events is not well explored.
  • A study examined the effects of gestational free and total T3 levels on issues like preeclampsia and preterm birth using data from over 33,000 mother-child pairs.
  • The results revealed complex associations between T3 levels and various risks, indicating that while TT3 may relate to certain outcomes, routine measurements during pregnancy might not significantly improve risk assessment for adverse outcomes.
View Article and Find Full Text PDF